What is Pleomorphic Sarcoma?

Pleomorphic sarcoma is a rare and aggressive soft tissue cancer. It usually develops in soft tissues such as connective tissue, muscle, nerves or blood vessels. The term "pleomorphic" refers to the heterogeneous nature of the tumor cells, which is different sizes and shapes. Pleomorphic sarcoma is usually diagnosed in advanced stages because it does not initially present any obvious symptoms.

Symptoms of Pleomorphic Sarcoma

This type of cancer can be noticed as a swelling or mass anywhere in the body. Symptoms may include:

• A painless, growing lump in any area of ​​the body (usually in areas such as the leg, arm, or abdomen)
• As the lump grows, it presses on surrounding tissues and causes pain
• Limited movement (especially if the tumor is near a joint)
• Color change or warmth in the lump under the skin

Causes and Risk Factors

The exact cause of Pleomorphic Sarcoma is unknown, but certain factors may increase the risk:

• Radiation therapy: People who have had high-dose radiation therapy in the past may be at an increased risk of developing Pleomorphic Sarcoma.
• Genetic factors: Certain genetic diseases may predispose to the development of sarcoma.
• Age and Gender: Pleomorphic sarcoma usually occurs in It is seen in individuals over the age of 50 and may be more common in men.

Diagnosis

Pleomorphic sarcoma is usually diagnosed by physical examination, imaging studies (ultrasound, MRI, or CT scan), and biopsy. The biopsy is necessary to determine the characteristic cellular structure of the tumor.

Treatment of Pleomorphic Sarcoma

Treatment varies depending on the stage of the cancer and the location of the tumor:

• Surgical intervention: The tumor is usually removed surgically. This is the most common and effective method of treatment.
• Radiation therapy: Radiation therapy may be administered before or after surgery. This decision must be made by an orthopedic tumor surgeon.
• Chemotherapy: Chemotherapy can be used for tumors that have metastasized or cannot be completely removed by surgical intervention.

Prognosis

The prognosis of Pleomorphic Sarcoma depends on the early diagnosis and treatment of the tumor. Tumors that are detected at an early stage and can be successfully removed generally have a good prognosis. However, the difficulty of treatment increases in advanced stages and metastasized cases.

Conclusion

Pleomorphic sarcoma is an aggressive and rare type of cancer. Early diagnosis and treatment by an orthopedic tumor surgeon increases the quality of life and improves the prognosis. It is important to consult a healthcare professional when a suspicious lump or mass is noticed.